Research Article
Echocardiographic Features of Cardiomyopathy in Emery-Dreifuss Muscular Dystrophy
Table 1
Baseline characteristics of the study population.
| | | EDMD patients, n = 41 | Healthy controls, n = 25 | value |
| | Age (years) | 43 (31–55) | 37 (36–44) | 0.17 | | Female (%) | 36.5 15/41 | 48.0; 12/25 | 0.81 | | BMI (kg/m2) | 20.8 (19.3–25.3) | 22.6 (20.4–24.1) | 0.37 | | BSA (m2) | 1.72 (1.55–1.83) | 1.77 (1.62–1.93) | 0.10 | | EMD (sporadic/familial) | 12/17 | | | | LMNA (sporadic/familial) | 7/5 | | | | Muscular involvement (mild/moderate/severe) | 18/19/4 | | | | NT-proBNP (pg/ml) | 74.6 (49.2–168.6) | 31.0 (15.6–66.2) | <0.001 | | NT-proANP (pg/ml) | 1.0 (0.8–1.9) | 0.8 (0.6–0.8) | <0.001 |
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BMI: body mass index; BSA: body surface area; EMD: mutation in EMD gen; LMNA: mutation in LMNA gene; NTpro-BNP: N-terminal prohormone B-type natriuretic peptide; NT-proANP: N-terminal prohormone A-type natriuretic peptide.
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