Efficiency, Safety, and Efficacy of High-Power Short-Duration Radiofrequency Ablation in Patients with Atrial Fibrillation

Table 2

The HPSD RF ablation settings and lesion endpoint in published clinical studies.

Study	Study type	Sample size	AF type	Catheter type	High power and dwell time		Contact force	Irrigation flow rate	Lesion endpoint
					Anterior wall	Posterior wall
Bunch et al. [21]	Controlled study	804	PAF and PsAF	Force-sensing catheter and non-force-sensing catheter	50 W/5–15s	50 W/2–5 s	5-2 g	30 ml/min	Local electrogram and dwell time
Winkle et al. [22]	Cohort study	1,250	PAF and PsAF and long-standing AF	Force-sensing catheter	50 W	50 W	10–40 g	—	Impedance drop, loss of pacing capture, and LSI
Chen et al. [23]	Cohort study	50	PAF and PsAF	STSF catheter	50 W	50 W	Minimum force 3 g	20 ml/min	AI
Vassallo et al. [24]	Controlled study	76	PAF and PsAF	Force-sensing catheter	50 W/6-8 s	45 W/6-8 s	10–20g(anterior)/5–10g(posterior)	35 ml/min	Impedance drop
Okamatsu et al. [25]	Controlled study	60	PAF and PsAF	STSF catheter	50 W	40 W	Minimum force 3g	—	AI
Berte et al. [26]	Controlled study	174	PAF and PsAF	STSF catheter	45 W	35 W	—	15 ml/min	AI
Kottmaier et al. [27]	Controlled study	197	PAF	Flexibility SE catheter	70 W/7 s	70 W/5 s	—	20 ml/min	Power and dwell time
Reddy et al. [28]	Cohort study	52	PAF	STSF catheter	90 W/4 s	90 W/4s	5–30 g	8 ml/min	Power and dwell time
Pambrun et al. [29]	Controlled study	100	PAF	Force-sensing catheter	50 W	40 W	Minimum force 10 g	—	Unipolar signal modification
Castrejón-Castrejón et al. [30]	Controlled study	95	PAF and PsAF	Force-sensing catheter	50–60 W	50–60 W	10 g	—	AI/LSI
Ejima et al. [31]	Controlled study	120	PAF	STSF catheter	50 W	50 W	10g	—	Unipolar signal modification
Yazaki et al. [32]	Controlled study	64	PAF	STSF catheter	50 W	50 W	—	—	Unipolar signal modification and dwell time
Yavin et al. [33]	Controlled study	224	PAF and PsAF	STSF catheter	45–50/15 s	45–50/8s	—	17 ml/min	Impedance drop
Ücer et al. [35]	Cohort study	25	PAF and PsAF	STSF catheter	50	50/6–10 s	10–15 g (posterior)/15–20 g (anterior)	15	Power and dwell time
Shin et al. [34]	RCT	150	PAF and PsAF	STSF catheter	50	50	20g	15	Power and dwell time

AI: ablation index; AF: atrial fibrillation; LSI: lesion size index; PAF: paroxysmal atrial fibrillation; PsAF: persistent atrial fibrillation; RF: radiofrequency; STSF : SmartTouch surround flow.