Research Article

Exercise Improves Endothelial Function via the lncRNA MALAT1/miR-320a Axis in Obese Children and Adolescents

Table 1

Comparisons of the baseline characteristics of obese children and adolescents before and after intervention.

CharacteristicsMatched group (n = 20)Exercise group (n = 40)
BeforeAfterBeforeAfter

Age (years)12.05 ± 2.2812.05 ± 2.2812.30 ± 2.61ns12.30 ± 2.61
Gender (males/females)13/713/728/12ns28/12
BMI (kg/m2)29.33 ± 1.1128.63 ± 0.9429.33 ± 1.29ns26.09 ± 1.05
Neck circumference (cm)39.30 ± 3.9939.10 ± 2.4940.50 ± 4.16ns36.80 ± 2.71
Waist circumference (cm)93.00 ± 2.2487.50 ± 1.9092.20 ± 2.65ns78.10 ± 2.85
Hip circumference (cm)99.40 ± 2.6796.20 ± 2.8699.60 ± 2.55ns90.80 ± 2.88
TC (mM)4.86 ± 0.264.06 ± 0.174.82 ± 0.19ns3.44 ± 0.16
TG (mM)1.73 ± 0.270.90 ± 0.081.79 ± 0.22ns0.77 ± 0.06
LDL-C (mg/dL)91.77 ± 13.9089.85 ± 13.7692.64 ± 14.30ns85.08 ± 13.60
HDL-C (mg/dL)46.44 ± 9.0449.72 ± 8.3048.78 ± 9.58ns51.12 ± 5.70
HOMA-IR3.17 ± 1.553.01 ± 1.423.34 ± 1.63ns2.51 ± 0.97

BMI, body mass index; TC, total cholesterol; TG, triglyceride; LDL-C, low-density lipoprotein cholesterol; HDL-C, high-density lipoprotein cholesterol; HOMA-IR, homeostatic model assessment-insulin resistance; ns, no significance when compared to the data before intervention in the matched group. when compared to the data before intervention in the exercise group. when compared to the data after intervention in the matched group.