Incremental Value of Genotype Bins over the HAS-BLED Score for the Prediction of Bleeding Risk in Warfarin-Treated Patients with Atrial Fibrillation

Figure 1

Bleeding events according to the genotype bins defining warfarin response and the HAS-BLED score. Highly sensitive responders were defined as carriers of the genotype bins CYP2C9 13 + VKORC1-1639A/A, CYP2C933 + VKORC1-1639 A/A, CYP2C933 + VKORC1-1639G/A, or CYP2C933 + VKORC1-1639G/G.