ANGPTL4 Attenuates Ang II-Induced Atrial Fibrillation and Fibrosis in Mice via PPAR Pathway

Figure 2

ANGPTL4 inhibits Ang II-induced atrial inflammation and apoptosis. (a) Representative image of HE staining in the atrial tissues of mice. The arrow indicates the infiltrated inflammatory cells. (b) TUNEL staining of atrial tissues for apoptosis detection. (c) The quantification of TUNEL positive cells in atrial tissues (n = 6 mice per group). RT-qPCR analyses of (d) IL-1β and (e) IL-6 levels in atrial tissues. n = 6 mice per group, n represents the number of animals.  < 0.001 vs. control group; ^### < 0.001 vs. Ang II group.

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