ANGPTL4 Attenuates Ang II-Induced Atrial Fibrillation and Fibrosis in Mice via PPAR Pathway

Figure 3

ANGPTL4 suppresses Ang II-induced atrial fibrosis. (a) Representative images of atrial fibrosis, which was stained with Masson trichrome. The fibrotic area was quantified. (b) Immunohistochemistry image of a-SMA. The percentage of a-SMA-positive cells is quantified. RT-qPCR analyses show the mRNA levels of collagen I and collagen III in atrial tissues. n = 6 mice per group, n represents the number of animals.  < 0.001 vs. control group; ^### < 0.001 vs. Ang II group.

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