Impact of MMP-9 Genetic Polymorphism and Concentration on the Development of Coronary Artery Disease in Ukrainian Population
Table 4
Association analysis between MMP-9 rs17576-single nucleotide polymorphism and CAD development.
Modela
ORc (95% CI)
ORa (95% CI)
Dominant
0.269
0.54 (0.181–1.609)
0.307
0.533 (0.159–1.781)
0.837
0.898 (0.322–2.507)
0.611
0.751 (0.249–2.265)
Recessive
0.945
1.056 (0.226–4.936)
0.52
0.533 (0.078–3.628)
0.758
0.792 (0.179–3.492)
0.787
0.793 (0.147–4.27)
Overdominant
0.242
0.522 (0.176–1.55)
0.498
0.647 (0.184–2.275)
—
—
—
—
Additive
AG vs. AA
0.224
0.485 (0.151–1.558)
0.337
0.53 (0.145–1.938)
0.903
0.935 (0.319–2.738)
0.67
0.781 (0.251–2.431)
GG vs. AA
0.722
0.741 (0.141–3.88)
0.338
0.317 (0.03–3.319)
0.74
0.762 (0.153–3.802)
0.949
0.936 (0.125–6.997)
CAD: coronary artery disease; : crude value; : value adjusted for age, sex, body mass index, the presence of hypertension, and smoking habits. aUpper row represents the results for the group with acute coronary syndrome, and the lower one for group with chronic coronary syndrome.
