Comparison of 6-Month and Prolonged Dual Antiplatelet Therapy after Percutaneous Coronary Intervention with Biodegradable Polymer Everolimus-Eluting Stent

Table 1

Baseline characteristics in the total population.

	Short-DAPT (N  = 483)	Prolonged-DAPT (N  = 310)	Standardized mean difference
Age	65.1 ± 11.0	65.8 ± 10.7	0.070	0.341
Male	357 (73.9)	223 (71.9)	0.044	0.595
Initial presentation			0.241	0.012
Stable angina	167 (34.6)	83 (26.8)
Unstable angina	201 (41.6)	143 (46.1)
Non–ST-segment elevation MI	70 (14.5)	37 (11.9)
ST-segment elevation MI	45 (9.3)	47 (15.2)
Atrial fibrillation	19 (3.9)	5 (1.6)	0.142	0.099
Body mass index	24.9 ± 3.1	24.4 ± 3.2	0.159	0.029
Hypertension	313 (64.8)	191 (61.6)	0.066	0.404
Diabetes	156 (32.3)	117 (37.7)	0.114	0.134
Diabetes on insulin	15 (3.1)	17 (5.5)	0.117	0.140
Current smoker	130 (26.9)	80 (25.8)	0.025	0.793
Dyslipidemia	240 (49.7)	139 (44.8)	0.097	0.207
Previous MI	37 (7.7)	29 (9.4)	0.061	0.477
Congestive heart failure	8 (1.7)	3 (1.0)	0.060	0.619
Peripheral vascular disease	13 (2.7)	14 (4.5)	0.098	0.237
Chronic kidney disease	18 (3.7)	23 (7.4)	0.161	0.033
Chronic kidney disease on dialysis	8 (1.7)	17 (5.5)	0.207	0.005
LV ejection fraction	60.9 ± 10.8	58.4 ± 12.5	0.174	0.003
Target vessel
(1) Left main	29 (6.0)	28 (9.0)	0.115	0.142
(2) Left anterior descending artery	279 (57.8)	186 (60.0)	0.045	0.582
(3) Left circumflex artery	140 (29.0)	90 (29.0)	0.001	>0.999
(4) Right coronary artery	160 (33.1)	122 (39.4)	0.130	0.087
Multivessel stent	104 (21.5)	83 (26.8)	0.123	0.107
Number of stents	1.5 ± 0.8	1.7 ± 0.9	0.205	0.005
Mean diameter of stent	3.2 ± 0.4	3.1 ± 0.4	0.115	0.117
Stent length	37.3 ± 25.4	41.6 ± 26.5	0.168	0.020
Overlapping stenting	65 (13.5)	47 (15.2)	0.026	0.570
Bifurcation stenting	5 (1.0)	6 (1.9)	0.065	0.455
Noncompliance balloon postdilatation	459 (95.0)	296 (95.5)	0.033	0.904
IVUS use	135 (28.0)	73 (23.5)	0.151	0.196
Femoral approach	140 (29.0)	114 (36.8)	0.166	0.027
Complete revascularization	315 (65.2)	175 (56.5)	0.180	0.016
Discharge medication
(1) Beta-blocker	305 (63.1)	178 (57.4)	0.117	0.124
(2) Calcium channel blocker	124 (25.7)	86 (27.7)	0.047	0.574
(3) ACE inhibitor or ARB	283 (58.6)	200 (64.5)	0.122	0.111
(4) Statin	444 (91.9)	299 (96.5)	0.194	0.016
PRECISE-DAPT score	14.3 ± 8.3	15.2 ± 8.4	0.101	0.165

ACE, angiotensin-converting enzyme; ARB, angiotensin-receptor blocker; DAPT, dual antiplatelet therapy; LV, left ventricle; MI, myocardial infarction.