Research Article

Comparison of 6-Month and Prolonged Dual Antiplatelet Therapy after Percutaneous Coronary Intervention with Biodegradable Polymer Everolimus-Eluting Stent

Table 2

Baseline characteristics of the matched population.

Short-DAPT (N = 283)Prolonged-DAPT (N = 283)Standardized mean difference

Age65.6 ± 11.066.0 ± 10.70.0350.676
Male203 (71.7)202 (71.4)0.008>0.999

Initial presentation0.0460.960
 Stable angina82 (29.0)79 (27.9)
 Unstable angina133 (47.0)131 (46.3)
 Non-ST-segment elevation MI33 (11.7)34 (12.0)
 ST-segment elevation MI35 (12.4)39 (13.8)

Atrial fibrillation6 (2.1)5 (1.8)0.026>0.999
Body mass index24.7 ± 3.124.5 ± 3.20.0740.378
Hypertension175 (61.8)178 (62.9)0.0220.862
Diabetes104 (36.7)103 (36.4)0.007>0.999
Diabetes on insulin13 (4.6)14 (4.9)0.017>0.999
Current smoker77 (27.2)72 (25.4)0.0400.703
Dyslipidemia132 (46.6)133 (47.0)0.007>0.999
Previous MI19 (6.7)23 (8.1)0.0540.630
Congestive heart failure1 (0.4)3 (1.1)0.0840.616
Peripheral vascular disease11 (3.9)12 (4.2)0.018>0.999
Chronic kidney disease15 (5.3)14 (4.9)0.016>0.999
Chronic kidney disease on dialysis8 (2.8)8 (2.8)<0.001>0.999
LV ejection fraction60.3 ± 11.159.4 ± 11.80.0780.355

Target vessel
 (1) Left main20 (7.1)26 (9.2)0.0780.442
 (2) Left anterior descending artery173 (61.1)172 (60.8)0.007>0.999
 (3) Left circumflex artery78 (27.6)81 (28.6)0.0240.852
 (4) Right coronary artery103 (36.4)103 (36.4)<0.001>0.999

Multivessel stent70 (24.7)73 (25.8)0.0240.847
Number of stents1.6 ± 0.91.6 ± 0.90.0410.627
Mean diameter of stent3.1 ± 0.43.1 ± 0.40.0350.674
Stent length40.2 ± 26.740.9 ± 26.50.0290.732
Femoral approach89 (31.4)95 (33.6)0.0450.654
Overlapping stenting43 (15.2)41 (14.5)0.0200.906
Bifurcation stenting3 (1.1)5 (1.8)0.0600.722
Noncompliance balloon postdilatation268 (94.7)269 (95.1)0.016>0.999
IVUS use82 (29.0)66 (23.3)0.1290.151
Complete revascularization156 (55.1)161 (56.9)0.0360.735

Discharge medication
 (1) Beta-blocker166 (58.7)163 (57.6)0.0210.865
 (2) Calcium channel blocker74 (26.1)76 (26.9)0.0160.924
 (3) ACE inhibitor or ARB178 (62.9)179 (63.3)0.007>0.999
 (4) Statin271 (95.8)272 (96.1)0.018>0.999

PRECISE-DAPT score15.0 ± 8.715.1 ± 8.40.0040.965

ACE, angiotensin-converting enzyme; ARB, angiotensin-receptor blocker; DAPT, dual antiplatelet therapy; LV, left ventricle; MI, myocardial infarction.