Research Article
Expression of TLR4 Is Upregulated in Patients with Sporadic Acute Stanford Type A Aortic Dissection
Table 2
Clinical and biochemical characteristics of the study participants.
| | All subjects | With TAAD | Without TAAD | value |
| Patients (n) | 102 | 49 | 53 | | Male sex (%) | 60 (58.8%) | 29 (59.2%) | 31 (58.5%) | 0.94 | Age (years) | 50 (46–58) | 51 (43–60) | 49 (47–58) | 0.85 | Smoking (n[%]) | 32 (31.4%) | 17 (34.7%) | 15 (28.3%) | 0.73 | Hypertension (n[%]) | 56 (54.9%) | 35 (71.4%) | 21 (39.6%) | 0.001 | D-dimer (mg/L) | 1.91 (0.89–5.42) | 5.41 (3.12–8.88) | 0.98 (0.52–1.26) | <0.001 | CCL5 (ng/mL) | 5.50 (5.10–6.70) | 5.10 (4.90–5.25) | 6.70 (6.10–7.10) | <0.001 | IL-1β (pg/mL) | 3.56 (2.49–4.12) | 3.90 (3.20–4.87) | 2.94 (2.05–3.77) | <0.001 | WBC (×109/L) | 9.45 (6.74–12.6) | 12.24 (9.26–13.86) | 7.36 (5.97–10.17) | <0.001 | TC (mmol/L) | 4.27 ± 0.08 | 4.26 ± 0.13 | 4.27 ± 0.11 | 0.99 | LDL-C (mol/L) | 2.65 (2.26–3.15) | 2.67 (2.56–3.13) | 2.45 (2.31–3.03) | 0.82 | HDL-C (mol/L) | 1.17 (1.05–1.38) | 1.14 (1.03–1.38) | 1.21 (1.08–1.39) | 0.44 |
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TAAD: acute Stanford type A aortic dissection; WBC: white blood cell; TC: total cholesterol; HDL-C: high-density lipoprotein cholesterol; LDL-C: low-density lipoprotein cholesterol; IL-1β: interleukin-1β; CCL5: CC chemokine ligand 5.
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