Research Article

Expression of TLR4 Is Upregulated in Patients with Sporadic Acute Stanford Type A Aortic Dissection

Table 2

Clinical and biochemical characteristics of the study participants.

All subjectsWith TAADWithout TAAD value

Patients (n)1024953
Male sex (%)60 (58.8%)29 (59.2%)31 (58.5%)0.94
Age (years)50 (46–58)51 (43–60)49 (47–58)0.85
Smoking (n[%])32 (31.4%)17 (34.7%)15 (28.3%)0.73
Hypertension (n[%])56 (54.9%)35 (71.4%)21 (39.6%)0.001
D-dimer (mg/L)1.91 (0.89–5.42)5.41 (3.12–8.88)0.98 (0.52–1.26)<0.001
CCL5 (ng/mL)5.50 (5.10–6.70)5.10 (4.90–5.25)6.70 (6.10–7.10)<0.001
IL-1β (pg/mL)3.56 (2.49–4.12)3.90 (3.20–4.87)2.94 (2.05–3.77)<0.001
WBC (×109/L)9.45 (6.74–12.6)12.24 (9.26–13.86)7.36 (5.97–10.17)<0.001
TC (mmol/L)4.27 ± 0.084.26 ± 0.134.27 ± 0.110.99
LDL-C (mol/L)2.65 (2.26–3.15)2.67 (2.56–3.13)2.45 (2.31–3.03)0.82
HDL-C (mol/L)1.17 (1.05–1.38)1.14 (1.03–1.38)1.21 (1.08–1.39)0.44

TAAD: acute Stanford type A aortic dissection; WBC: white blood cell; TC: total cholesterol; HDL-C: high-density lipoprotein cholesterol; LDL-C: low-density lipoprotein cholesterol; IL-1β: interleukin-1β; CCL5: CC chemokine ligand 5.