Research Article
Atorvastatin Inhibits Ferroptosis of H9C2 Cells by regulatingSMAD7/Hepcidin Expression to Improve Ischemia-Reperfusion Injury
Figure 4
ATV inhibited ferroptosis in H9C2 cells through the SMAD7/hepcidin pathway. (a–b).The relative expression of SMAD7, hepcidin, IRPs, TFRC1, FTH, and FPN1 were detected by qPCR. (c). ELISA was utilized to determine the concentration of total iron and Fe2+. (d). The cell vitality was measured by CCK8. vs. the H/R group. ns: no significant difference vs. the H/R + SMAD7i group.
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