Research Article
Distinguishing Cardiac Amyloidosis and Hypertrophic Cardiomyopathy by Thickness and Myocardial Deformation of the Right Ventricle
Table 2
Cardiac function and myocardial strain in CA and HCM patients.
| Parameters | Normal controls (n = 30) | HCM (n = 60) | CA (n = 60) | value (CA vs HCM) |
| RVEF% | 57.1 ± 9.1 | 51.6 ± 13.5 | 41.5 ± 16.5∗∗∗ | <0.001 | RVEDV-index (ml/m2) | 60.1 ± 16.4 | 53.7 ± 11.4 | 58.3 ± 19.9 | 0.556 | RVESV-index (ml/m2) | 25.3 ± 7.6 | 25.9 ± 8.9 | 34.4 ± 16.3∗∗ | 0.001 |
| Radical | RV-PS (%) | 31.3 ± 7.6 | 23.5 ± 12.1∗∗ | 12.1 ± 6.9∗∗∗ | <0.001 | RV-PSSR (1/s) | 2.7 ± 1.5 | 1.9 ± 2.4 | 1.2 ± 1.2∗∗∗ | 0.097 | RV-PDSR (1/s) | −2.7 ± 1.5 | −1.5 ± 0.8∗∗∗ | −1.1 ± 0.8∗∗∗ | 0.079 |
| Circumferential | RV-PS (%) | −13.7 ± 2.5 | −5.6 ± 3.5∗∗∗ | −3.4 ± 2.2 | <0.001 | RV-PSSR (1/s) | −0.7 ± 0.4 | −0.7 ± 0.4 | −0.6 ± 0.5 | 0.086 | RV-PDSR (1/s) | 0.9 ± 0.5 | 0.6 ± 0.3 | 0.5 ± 0.2# | 0.048 |
| Longitudinal | RV-PS (%) | −14.23 ± 3.0 | 11.1 ± 4.9∗∗∗ | −4.6 ± 2.3∗∗∗ | <0.001 | RV-PSSR (1/s) | −0.6 ± 0.4 | −0.7 ± 0.5 | −0.9 ± 0.4 | 0.634 | RV-PDSR (1/s) | 0.7 ± 0.5 | 0.8 ± 0.4 | 0.8 ± 0.4 | 0.546 | RVT (mm) | 4.0 ± 1.1 | 5.9 ± 1.3∗∗∗ | 7.8 ± 2.1∗∗∗ | <0.001 |
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CA, cardiac amyloidosis; HCM, hypertrophic cardiomyopathy; RVEF, right ventricular ejection fraction; EDV, end-diastolic volume; ESV, end-systolic volume; RV, right ventricular, PS, peak strain; PSSR, peak systolic strain rate; PDSR, peak diastolic strain rate; RVT, right ventricular thickness. , , and versus controls. |