Research Article

Distinguishing Cardiac Amyloidosis and Hypertrophic Cardiomyopathy by Thickness and Myocardial Deformation of the Right Ventricle

Table 2

Cardiac function and myocardial strain in CA and HCM patients.

ParametersNormal controls (n = 30)HCM (n = 60)CA (n = 60) value (CA vs HCM)

RVEF%57.1 ± 9.151.6 ± 13.541.5 ± 16.5∗∗∗<0.001
RVEDV-index (ml/m2)60.1 ± 16.453.7 ± 11.458.3 ± 19.90.556
RVESV-index (ml/m2)25.3 ± 7.625.9 ± 8.934.4 ± 16.3∗∗0.001

Radical
RV-PS (%)31.3 ± 7.623.5 ± 12.1∗∗12.1 ± 6.9∗∗∗<0.001
RV-PSSR (1/s)2.7 ± 1.51.9 ± 2.41.2 ± 1.2∗∗∗0.097
RV-PDSR (1/s)−2.7 ± 1.5−1.5 ± 0.8∗∗∗−1.1 ± 0.8∗∗∗0.079

Circumferential
RV-PS (%)−13.7 ± 2.5−5.6 ± 3.5∗∗∗−3.4 ± 2.2<0.001
RV-PSSR (1/s)−0.7 ± 0.4−0.7 ± 0.4−0.6 ± 0.50.086
RV-PDSR (1/s)0.9 ± 0.50.6 ± 0.30.5 ± 0.2#0.048

Longitudinal
RV-PS (%)−14.23 ± 3.011.1 ± 4.9∗∗∗−4.6 ± 2.3∗∗∗<0.001
RV-PSSR (1/s)−0.6 ± 0.4−0.7 ± 0.5−0.9 ± 0.40.634
RV-PDSR (1/s)0.7 ± 0.50.8 ± 0.40.8 ± 0.40.546
RVT (mm)4.0 ± 1.15.9 ± 1.3∗∗∗7.8 ± 2.1∗∗∗<0.001

CA, cardiac amyloidosis; HCM, hypertrophic cardiomyopathy; RVEF, right ventricular ejection fraction; EDV, end-diastolic volume; ESV, end-systolic volume; RV, right ventricular, PS, peak strain; PSSR, peak systolic strain rate; PDSR, peak diastolic strain rate; RVT, right ventricular thickness. , , and versus controls.