Research Article
Distinguishing Cardiac Amyloidosis and Hypertrophic Cardiomyopathy by Thickness and Myocardial Deformation of the Right Ventricle
Table 4
Cardiac function and myocardial strain in CA and HCM patients with or without RV hypertrophy.
| | Parameters | RV hypertrophy | Without RV hypertrophy | | HCM (n = 23) | CA (n = 42) | value | HCM (n = 37) | CA (n = 18) | value |
| | RVEF% | 49.1 ± 14.5 | 38.3 ± 15.7 | 0.002 | 53.3 ± 12.7 | 49.9 ± 16.5 | 0.102 | | RVEDV-index (ml/m2) | 56.1 ± 12.5 | 61.2 ± 18.8 | 0.065 | 52.1 ± 10.6 | 50.9 ± 22.2 | 0.165 | | RVESV-index (ml/m2) | 28.4 ± 9.1 | 38.4 ± 16.9 | 0.045 | 24.3 ± 8.5 | 24.1 ± 9.2 | 0.096 |
| | Radical | | RV-GPS (%) | 22.8 ± 11.9 | 10.5 ± 6.6 | <0.001 | 23.9 ± 12.2 | 15.7 ± 6.1 | 0.021 | | RV-PSSR (1/s) | 1.6 ± 0.7 | 1.2 ± 1.0 | 0.157 | 2.1 ± 0.3 | 1.2 ± 0.5 | 0.197 | | RV-PDSR (1/s) | −1.4 ± 0.8 | −1.0 ± 0.7 | 0.150 | −1.6 ± 0.9 | −1.4 ± 0.7 | 0.443 |
| | Circumferential | | RV-GPS (%) | −6.4 ± 4.2 | −3.1 ± 2.2 | <0.001 | −5.1 ± 3.1 | −3.4 ± 1.8 | 0.061 | | RV-PSSR (1/s) | −0.7 ± 0.2 | −0.6 ± 0.3 | 0.538 | −0.7 ± 0.5 | −0.5 ± 0.3 | 0.246 | | RV-PDSR (1/s) | 0.6 ± 0.3 | 0.5 ± 0.2 | 0.375 | 0.6 ± 0.3 | 0.6 ± 0.3 | 0.421 |
| | Longitudinal | | RV-GPS (%) | −11.5 ± 5.1 | −4.1 ± 2.1 | <0.001 | −10.9 ± 4.8 | −5.8 ± 2.4 | <0.001 | | RV-PSSR (1/s) | −0.6 ± 0.5 | −0.8 ± 0.5 | 0.159 | −0.9 ± 0.4 | −0.9 ± 0.3 | 0.564 | | RV-PDSR (1/s) | 0.8 ± 0.4 | 0.8 ± 0.4 | 0.638 | 0.8 ± 0.4 | 0.9 ± 0.4 | 0.954 | | RVT (mm) | 7.0 ± 0.8 | 8.7 ± 1.5 | 0.001 | 5.1 ± 1.0 | 5.5 ± 1.3 | 0.120 |
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CA, cardiac amyloidosis; HCM, hypertrophic cardiomyopathy; RVEF, right ventricular ejection fraction; EDV, end-diastolic volume; ESV, end-systolic volume; RV, right ventricular; PS, peak strain; PSSR, peak systolic strain rate; PDSR, peak diastolic strain rate; RVT, right ventricular thickness.
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