TMAO-Activated Hepatocyte-Derived Exosomes Are Widely Distributed in Mice with Different Patterns and Promote Vascular Inflammation

Figure 2

Verification of the top 10 hub genes. (a–e) TMAO remarkably enhanced the mRNA expressions of Phgdh, Mdh2, Echs1, Rap2a, and Gpd1l and (f) reduced Slc3a2 levels. (g–j) Hyou1, Hspa9, Psat1, and Pck2 remained unchanged. qPCR was used to determine the mRNA expressions (n = 3).  < 0.05 vs. the blank control group. ns indicates not significant.

(a)

(b)

(c)

(d)

(e)

(f)

(g)

(h)

(i)

(j)