The Effect of Antihypertensive Drugs on NADH in Newly Diagnosed Primary Hypertension

Table 2

Summary of continuous measures for hypertensive patients assigned to amlodipine at 5 mg QD. values of the paired analysis of continuous data with a nonparametric Wilcoxon test for comparison of results before and after the six-week treatment.

Parameter	Median v1 (Q1–Q3)	Median v2 (Q1–Q3)
DTHR (beats/min)	81.61 (75.95–87.46)	81.90 (74.72–87.54)	0.2046
DTSBP (mmHg)	145.22 (141.85–154.36)	140.98 (136.55–146.90)	0.0106
DTDBP (mmHg)	87.92 (83.59–92.51)	83.37 (79.43–88.27)	0.0024
NTHR (beats/min)	61.54 (56.36–68.58)	65.86 (60.64–70.33)	0.4979
NTSBP (mmHg)	121.53 (113.81–130.17)	117.00 (110.63–120.33)	0.0143
NTDBP (mmHg)	71.43 (66.00–76.71)	68.88 (66.47–72.00)	0.0987
24-hHR (beats/min)	78.01 (72.81–85.27)	78.09 (72.46–84.27)	0.3945
24-hSBP (mmHg)	141.18 (138.24–148.63)	135.78 (133.58–142.01)	0.0087
24-hDBP (mmHg)	83.44 (80.70–88.84)	80.08 (77.69–85.35)	0.0046
Bmean (kFU)	698.76 (612.07–980.10)	650.87 (521.34–947.29)	0.1592
FImax (kFU)	764.51 (657.05–1020.35)	685.47 (591.92–1074.57)	0.4549
FRmin (kFU)	583.94 (512.90–837.28)	545.06 (453.11–756.72)	0.2891
Imax (kFU)	46.86 (29.45–85.08)	64.80 (32.17–88.77)	0.6639
Rmin (kFU)	136.79 (73.63–157.55)	105.81 (73.58–141.26)	0.0918
IRampl (kFU)	180.57 (106.74–222.38)	185.74 (118.52–210.54)	0.4761
CImax	0.32 (0.21–0.40)	0.38 (0.31–0.44)	0.2172

Bmean, mean fluorescence recorded before ischemia as the baseline value; FImax, the maximal fluorescence above the baseline during ischemia; FRmin, the minimal fluorescence below the baseline during reperfusion; Imax, the difference between FImax and Bmean; IRampl, the difference between FImax and FRmin; Rmin, the difference between Bmean and FRmin; CImax, Imax/IRampl rate; 24-hSBP, 24-hour systolic blood pressure; 24-hDBP, 24-hour diastolic blood pressure; 24-hPR, 24-hour pulse rate; DTSBP, day time systolic blood pressure; DTDBP, day time diastolic blood pressure; DTPR, day time pulse rate; NTSBP, night time systolic blood pressure; NTDBP, night time diastolic blood pressure; and NTPR, night time pulse rate.