The Effect of Antihypertensive Drugs on NADH in Newly Diagnosed Primary Hypertension

Table 3

Summary of continuous measures for hypertensive patients assigned to perindopril at 5 mg QD. values of the paired analysis of continuous data with a nonparametric Wilcoxon test for comparison of results before and after the six-week treatment.

Parameter	Median v1 (Q1–Q3)	Median v2 (Q1–Q3)
DTHR (beats/min)	78.85 (74.20–87.28)	81.63 (78.03–84.99)	0.5678
DTSBP (mmHg)	147.73 (141.83–156.44)	135.93 (133.37–139.86)	<0.0001
DTDBP (mmHg)	87.76 (82.28–91.98)	82.03 (78.62–83.93)	0.0002
NTHR (beats/min)	66.69 (58.26–71.43)	64.07 (58.15–68.93)	0.1956
NTSBP (mmHg)	121.00 (114.25–135.41)	112.80 (106.18–124.07)	0.0062
NTDBP (mmHg)	70.77 (63.30–78.86)	64.10 (60.83–67.68)	0.0053
24-hHR (beats/min)	75.93 (71.74–84.13)	75.95 (74.88–82.38)	0.9217
24-hSBP (mmHg)	142.14 (136.85–149.74)	130.08 (126.76–135.78)	<0.0001
24-hDBP (mmHg)	83.15 (78.51–89.06)	78.08 (73.76–80.81)	0.0001
Bmean (kFU)	573.97 (448.95–709.54)	603.27 (492.43–932.26)	0.3321
FImax (kFU)	601.06 (499.50–778.15)	646.14 (524.99–1034.60)	0.418
FRmin (kFU)	487.64 (375.46–600.34)	478.53 (409.05–782.31)	0.3736
Imax (kFU)	50.03 (30.78–79.26)	48.44 (32.79–70.67)	0.9843
Rmin (kFU)	90.97 (64.25–120.60)	99.04 (73.29–129.76)	0.4413
IRampl (kFU)	131.94 (113.13–183.81)	147.48 (111.40–192.99)	0.6507
CImax	0.35 (0.25–0.44)	0.34 (0.27–0.40)	0.4653

Bmean, mean fluorescence recorded before ischemia as the baseline value; FImax, the maximal fluorescence above the baseline during ischemia; FRmin, the minimal fluorescence below the baseline during reperfusion; Imax, the difference between FImax and Bmean; IRampl, the difference between FImax and FRmin; Rmin, the difference between Bmean and FRmin; CImax, Imax/IRampl rate; 24-hSBP, 24-hour systolic blood pressure; 24-hDBP, 24-hour diastolic blood pressure; 24-hPR, 24-hour pulse rate; DTSBP, day time systolic blood pressure; DTDBP, day time diastolic blood pressure; DTPR, day time pulse rate; NTSBP, night time systolic blood pressure; NTDBP, night time diastolic blood pressure; and NTPR, night time pulse rate.