The Effect of Antihypertensive Drugs on NADH in Newly Diagnosed Primary Hypertension

Table 4

Summary of continuous measures for hypertensive patients assigned to nebivolol at 5 mg QD. values of the paired analysis of continuous data with a nonparametric Wilcoxon test for comparison of results before and after the six-week treatment.

Parameter	Median v1 (Q1–Q3)	Median v2 (Q1–Q3)
DTHR (beats/min)	85.25 (80.67–91.59)	73.79 (66.34–84.34)	<0.0001
DTSBP (mmHg)	148.38 (142.81–150.98)	134.13 (129.21–139.13)	0.0002
DTDBP (mmHg)	88.76 (85.24–92.10)	79.25 (76.65–83.06)	0.0004
NTHR (beats/min)	67.87 (63.24–79.03)	59.08 (53.44–67.80)	0.0003
NTSBP (mmHg)	116.99 (108.50–127.35)	108.28 (103.93–118.27)	0.0003
NTDBP (mmHg)	69.36 (65.55–73.45)	64.19 (58.69–66.94)	0.001
24-hHR (beats/min)	82.97 (76.49–87.01)	71.00 (64.73–80.90)	0.0001
24-hSBP (mmHg)	142.23 (137.20–145.74)	128.89 (124.24–136.22)	0.0001
24-hDBP (mmHg)	84.20 (81.51–87.89)	76.40 (73.80–79.56)	0.0002
Bmean (kFU)	698.38 (480.04–790.76)	708.93 (479.29–869.10)	0.498
FImax (kFU)	743.52 (519.45–909.43)	745.37 (511.24–980.34)	0.7285
FRmin (kFU)	553.30 (404.35–624.36)	592.01 (416.14–725.93)	0.2774
Imax (kFU)	50.96 (17.29–89.98)	44.16 (16.28–80.50)	0.8408
Rmin (kFU)	132.77 (73.64–158.75)	115.55 (60.18–150.60)	0.0696
IRampl (kFU)	203.45 (98.85–235.99)	158.62 (90.14–223.12)	0.165
CImax	0.30 (0.22–0.39)	0.31 (0.24–0.37)	1

Bmean, mean fluorescence recorded before ischemia as the baseline value; FImax, the maximal fluorescence above the baseline during ischemia; FRmin, the minimal fluorescence below the baseline during reperfusion; Imax, the difference between FImax and Bmean; IRampl, the difference between FImax and FRmin; Rmin, the difference between Bmean and FRmin; CImax, Imax/IRampl rate; 24-hSBP, 24-hour systolic blood pressure; 24-hDBP, 24-hour diastolic blood pressure; 24-hPR, 24-hour pulse rate; DTSBP, day time systolic blood pressure; DTDBP, day time diastolic blood pressure; DTPR, day time pulse rate; NTSBP, night time systolic blood pressure; NTDBP, night time diastolic blood pressure; and NTPR, night time pulse rate.