Research Article
Prospective Longitudinal Characterization of the Relationship between Diabetes and Cardiac Structural and Functional Changes
| | Variable | Baseline (n = 32) | Follow-up (n = 32) | value |
| | LV end-diastolic volume (ml) | 159 ± 29 | 145 ± 22 | 0.005 | | LV end-diastolic volume index (ml/m2) | 78 ± 12 | 73 ± 10 | 0.02 | | LV end-systolic volume (ml) | 64 ± 16 | 65 ± 19 | 0.5 | | LV end-systolic volume index (ml/m2) | 31 ± 7 | 33 ± 9 | 0.3 | | LV stroke volume (ml) | 95 ± 20 | 80 ± 14 | 0.001 | | LV ejection fraction (%) | 60 ± 7 | 55 ± 8 | 0.0001 | | ΔLVEF (%) | −(5.66 ± 4.38) | | LV mass (gm) | 102 ± 17 | 94 ± 16 | 0.01 | | LV mass index (gm/m2) | 51 ± 8 | 47 ± 8 | 0.04 | | LV mass to LV end-diastolic volume (gm/ml) | 0.65 ± 0.12 | 0.66 ± 0.14 | 0.8 | | Global longitudinal strain (%, negative) | 13.06 ± 2.05 | 11.74 ± 2.54 | 0.8 | | Peak diastolic circumferential strain rate (1/s) | 0.98 ± 0.28 | 1.04 ± 0.23 | 0.4 | | Peak diastolic longitudinal strain rate (1/s) | 0.86 ± 0.19 | 0.69 ± 0.17 | 0.1 | | RV end-diastolic volume (ml) | 166 ± 33 | 142 ± 25 | 0.03 | | RV end-diastolic volume index (ml/m2) | 82 ± 14 | 71 ± 12 | 0.0001 | | RV end-systolic volume (ml) | 76 ± 18 | 70 ± 16 | 0.05 | | RV end-systolic volume index (ml/m2) | 37 ± 8 | 35 ± 8 | 0.1 | | RV stroke volume (ml) | 91 ± 20 | 72 ± 15 | <0.0001 | | RV ejection fraction (%) | 55 ± 5 | 51 ± 7 | 0.003 | | ΔRVEF (%) | −(6.69 ± 4.15) | | LA maximum volume (ml) | 88 ± 17 | 67 ± 21 | 0.0001 | | LA ejection fraction (%) | 58 ± 6 | 56 ± 9 | 0.4 | | Extracellular volume (%) | 24.96 ± 3.02 | 24.10 ± 2.66 | 0.3 |
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Values are mean±standard deviations or percentages. signifies . CMR-cardiac magnetic resonance imaging; n-numbers; LV-left ventricle; ml-milliliters; m-meter; ΔLVEF-change in LV ejection fraction; gm-grams; s-seconds; RV-right ventricle; ΔRVEF-change in RV ejection fraction; LA-left atrium. |
