Serial Changes in Exercise Capacity, NT-proBNP, and Adiponectin in Patients with Acute Coronary Syndrome before and after Phase II Rehabilitation as well as at the 12-Month Follow-Up
Table 1
Basic clinical data in patients before and after CR as well as at 12 months.
Basic characteristics
Age (years)
56 ± 10
M/F
69/12
Diabetes mellitus
11 (13.6)
Hypertension
60 (74.1)
Hyperlipidemia
60 (74.1)
Coronary artery disease
1 vessel
27
2 vessels
35
3 vessels
19
ST-elevation MI
68 (83.9)
Non-ST-elevation MI
10 (12.3)
Unstable angina
3 (3.7)
Revascularization at 12-month follow-up
Re-PCI/stent
18
CABG
3
Before CR
After CR
12-month
Risk factors
Smoking
66 (81.5)
0 (0.0)a
15 (18.5)b,c
Weight (kg)
85.4 ± 14.7
84.6 ± 14.0
87.1 ± 15.2b,c
BMI (kg/m2)
27.8 ± 3.6
27.5 ± 3.5
28.6 ± 3.8b,c
Cholesterol (mmol/l)
5.1 (4.3–6.1)
4.3 ± 1.2a
4.5 ± 1.0b
HDL (mmol/l)
1.2 ± 0.3
1.3 ± 0.4
1.2 ± 0.3
LDL (mmol/l)
2.4 ± 0.8
2.3 ± 0.8
2.5 ± 0.8
Triglycerides (mmol/l)
2.0 (1.1–2.9)
1.5 (0.8–2.6)
1.5 (1.0–2.4)
Glucose (mg/dl)
89 (72–115)
87 (81–102)
94 (81–107)
CRP (µg/ml)
12.96 (7.25–18.76)
2.04 (0.49–5.61)a
2.28 (0.42–4.37)b
Creatinine (µmol/l)
96 (84–111)
94 (87–141)
94 (88–113)
Medication
Aspirin
79 (97.5)
80 (98.8)
79 (97.5)
ACE inhibitor
71 (87.7)
68 (84.0)
58 (71.6)b
Beta-blocker
79 (97.5)
77 (95.1)
69 (85.2)b,c
Ca2+ antagonist
3 (3.7)
3 (3.7)
4 (4.9)
Statin
77 (95.1)
79 (97.5)
66 (81.5)b,c
LV dysfunction
EF < 50%
27 (33.3)
32 (39.5)
16 (19.8)c
Mild: EF 41–50%
18 (22.2)
23 (28.4)
12 (14.8)c
Moderate: EF 30–40%
8 (9.9)
8 (9.9)
1 (1.2)b,c
Severe: EF <30%
1 (1.2)
1 (1.2)
3 (3.7)
Quality of life
Scores
70 (50–80)
80 (67–90)a
80 (60–90)b
Data are presented as mean ± SD or median (interquartile) or number (%) of patients. a,bCompared to before CR, < 0.05; cCompared to after CR, < 0.05; MI, myocardial infarction; PCI, percutaneous coronary intervention; CABG, coronary-artery-bypass graph; LV, left ventricle; EF, ejection fraction; CR, cardiac rehabilitation; BMI, body mass index; HDL, high-density lipoprotein cholesterol; LDL, low-density lipoprotein cholesterol; CRP, C-reactive protein; ACE, angiotensin converting enzyme.
