Research Article

Synthesized 18-Lead Electrocardiogram in Diagnosing Posterior Stemi-Equivalent Acute Coronary Syndrome in Patients with NSTEMI

Table 1

Patient characteristics.

Total n = 219sV7-9 STE n = 16No STE n = 203

Baseline characteristics
Age, years68.8 (11.9)63.7 (14.3)69.2 (11.7)0.07
Men, n (%)179 (81.7)12 (75.0)167 (82.3)0.70
Body mass index, kg/m224.2 (22.1, 26.1)26.1 (23.4, 28.4)24.1 (22.1, 25.8)0.07
Current smoking, n (%)72 (32.9)6 (37.5)66 (32.5)0.90
Diabetes, n (%)102 (46.6)9 (56.2)93 (46.0)0.60
Hypertension, n (%)151 (68.9)13 (81.2)138 (68.0)0.41
Dyslipidemia, n (%)113 (51.6)8 (50.0)105 (51.7)1.0
Left ventricular EF, %57.3 (10.0)60.0 (8.6)57.2 (10.2)0.17
Previous MI, n (%)46 (21.0)1 (6.2)45 (22.2)0.24
Aspirin at baseline, n (%)62 (28.36)3 (18.8)59 (29.1)0.55
Chest symptom on admission, n (%)206 (94.1)16 (100.0)190 (93.6)0.62

ECG characteristics
V1-3 STD, n (%)19 (8.7)5 (31.2)14 (6.9)0.01
V4-6 STD, n (%)63 (28.8)3 (18.8)60 (29.6)0.57
I, aVL STD, n (%)12 (5.5)0 (0)12 (5.9)1.0
II, III, aVF STD, n (%)27 (12.3)0 (0)27 (13.3)0.25
aVR STD, n (%)1 (3.4)0 (0)1 (0.5)1.0
Synthesized V7-9 STD, n (%)10 (4.6)0 (0)10 (4.9)1.0
Atrial fibrillation, n (%)16 (7.3)0 (0)16 (7.9)0.54

Biochemical analysis
hs-cTnI on admission, ng/L436 (154, 1883)1055 (380, 6474)394 (150, 1799)0.06
NT-proBNP on admission, pg/mL530 (155, 1829)263 (150, 1086)581 (161, 2017)0.31
Peak hs-cTnI, ng/L5759 (2060, 19795)36203 (17255, 93105)4895 (1913, 15797)<0.01

Risk assessment on admission
Killip grade, %0.71
119515 (93.8)180 (88.7)
216 (7.3)1 (6.2)15 (7.4)
38 (3.7)0 (0)8 (3.9)
40 (0)0 (0)0 (0)
TIMI score4 (3, 5)4 (3, 5)4 (3, 4)0.18
GRACE score144 (119, 172)113 (94, 142)145 (122, 173)0.01

Values are n (%) for categorical variables and mean (SD) or median [IQR] for continuous variables. Categorical variables were compared using the chi-square test or Fisher’s exact test. Continuous variables were compared using Student’s t-test or the Mann–Whitney U test, accordingly. STE, ST-segment elevation; STD, ST-segment depression; EF, ejection fraction; MI, myocardial infarction; hs-cTnI, cardiac troponin I; NT-pro BNP, N terminal pro B type natriuretic peptide; TIMI, thrombolysis in myocardial infarction; GRACE, Global Registry of Acute Coronary Events.