Identification of Plasma Exosomes hsa_circ_0001360 and hsa_circ_0000038 as Key Biomarkers of Coronary Heart Disease

Figure 4

Exosome identification and key circRNA validation. (a) The morphological characteristics of the exosomes were assessed by transmission electron microscopy. (b) The size distribution of the exosomes was measured by nanoparticle tracking analysis. (c) Validation of the key circRNAs in normal and CHD samples. ^∗indicates statistical significance, with a P value less than 0.05. (d) ROC curve analysis. (e and f) The downstream miRNA and mRNA networks of hsa_circ_0001360 and hsa_circ_0000038.

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