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Disease Markers
Volume 21 (2005), Issue 2, Pages 57-59
http://dx.doi.org/10.1155/2005/340186

CYP1A1 Genetic Polymorphisms in Ecuador, South America

César Paz-y-Miño,1,2 Melissa Arévalo,1 María José Muñoz G.,1 and Paola. E. Leone1,2

1Laboratorio de Genética Molecular y Citogenética Humana, Escuela de Biologiá, Quito, Ecuador
2Facultad of Medicina, Pontificia Universidad Católica del Ecuador, Ecuador

Received 24 May 2005; Accepted 24 May 2005

Copyright © 2005 Hindawi Publishing Corporation. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Abstract

A total of 108 individuals from the Ecuadorian population from rural and urban places were analyzed for two CYP1A1 gene polymorphisms. The frequency of the val allele at codon 462 was 0.50, while the frequency of the Msp I restriction site, m2 allele at the T6235C position was 0.70. These polymorphisms in Ecuador have higher frequencies if we compare with others around the world, with the exception of some South American population in Brazil and Chile.