Disease Markers

Disease Markers / 2009 / Article
Special Issue

Circulating Biomarkers in Cardiovascular Disease

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Volume 26 |Article ID 143680 | https://doi.org/10.3233/DMA-2009-0636

Diederik F. van Wijk, Erik S. G. Stroes, John J. P. Kastelein, "Lipid Measures and Cardiovascular Disease Prediction", Disease Markers, vol. 26, Article ID 143680, 8 pages, 2009. https://doi.org/10.3233/DMA-2009-0636

Lipid Measures and Cardiovascular Disease Prediction

Received15 Sep 2009
Accepted15 Sep 2009

Abstract

Traditional lipid measures are the cornerstone of risk assessment and treatment goals in cardiovascular prevention. Whereas the association between total, LDL-, HDL-cholesterol and cardiovascular disease risk has been generally acknowledged, the rather poor capacity to distinguish between patients who will and those who will not develop cardiovascular disease has prompted the search for further refinement of these traditional measures. A thorough understanding of lipid metabolism is mandatory to understand recent developments in this area. After a brief overview of lipid metabolism we will discuss the epidemiological data of total, LDL- and HDL-cholesterol and focus on recent advances in measurements of these lipoproteins. In addition we will discuss the role of triglycerides and the apolipoprotein B–A-I ratio on the incidence of cardiovascular disease.

Copyright © 2009 Hindawi Publishing Corporation. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.


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