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Disease Markers
Volume 29, Issue 3-4, Pages 151-156
http://dx.doi.org/10.3233/DMA-2010-0740

DOCK8 Immune Deficiency as a Model for Primary Cytoskeletal Dysfunction

Sean A. McGhee and Talal A. Chatila

Department of Pediatrics, David Geffen School of Medicine at UCLA, Los Angeles, CA, USA

Received 14 December 2010; Accepted 14 December 2010

Copyright © 2010 Hindawi Publishing Corporation. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Citations to this Article [20 citations]

The following is the list of published articles that have cited the current article.

  • Karoly Lakatos, Rene Geyeregger, Susanne Matthes-Martin, Christina Peters, Alexandra Ruemmele-Waibel, Ellen D. Renner, Julie Sawalle-Belohradsky, Ernst Horcher, Anita Lawitschka, Bernd H. Belohradsky, Georg Mann, Michael H. Albert, Bernd Ausserer, Heidrun Boztug, and Caecilia Karitnig-Weiss, “Clinical and Immunological Correction of DOCK8 Deficiency by Allogeneic Hematopoietic Stem Cell Transplantation Following a Reduced Toxicity Conditioning Regimen,” Pediatric Hematology And Oncology, vol. 29, no. 7, pp. 585–594, 2012. View at Publisher · View at Google Scholar
  • Maria L. Chanco Turner, Steven M. Holland, Emily Y. Chu, Huie Jing, Alexandra F. Freeman, Edward W. Cowen, Joie Davis, and Helen C. Su, “Cutaneous Manifestations of DOCK8 Deficiency Syndrome,” Archives of Dermatology, vol. 148, no. 1, pp. 79–84, 2012. View at Publisher · View at Google Scholar
  • Beáta Tóth, Zsuzsanna Pistár, Gabriella Csorba, István Balogh, Tímea Kovács, Melinda Erdős, and László Maródi, “Novel dedicator of cytokinesis 8 mutations identified by multiplex ligation-dependent probe amplification,” European Journal of Haematology, 2013. View at Publisher · View at Google Scholar
  • Luis E Arias-Romero, and Jonathan Chernoff, “Targeting Cdc42 in cancer,” Expert Opinion on Therapeutic Targets, pp. 1–11, 2013. View at Publisher · View at Google Scholar
  • Elizabeth M. Todd, Lauren E. Deady, and Sharon Celeste Morley, “Intrinsic T- and B-cell defects impair T-cell-dependent antibody responses in mice lacking the actin-bundling protein L-plastin,” European Journal of Immunology, vol. 43, no. 7, pp. 1735–1744, 2013. View at Publisher · View at Google Scholar
  • Hyoungjun Ham, Sabrice Guerrier, Jung Jin Kim, Renee A. Schoon, Erik L. Anderson, Michael J. Hamann, Zhenkun Lou, and Daniel D. Billadeau, “Dedicator of cytokinesis 8 interacts with talin and Wiskott-Aldrich syndrome protein to regulate NK cell cytotoxicity,” Journal of Immunology, vol. 190, no. 7, pp. 3661–3669, 2013. View at Publisher · View at Google Scholar
  • Julia Oh, Alexandra F. Freeman, Morgan Park, Robert Sokolic, Fabio Candotti, Steven M. Holland, Julia A. Segre, and Heidi H. Kong, “The altered landscape of the human skin microbiome in patients with primary immunodeficiencies,” Genome Research, vol. 23, no. 12, pp. 2103–2114, 2013. View at Publisher · View at Google Scholar
  • Tim Lämmermann, and Ronald N. Germain, “The multiple faces of leukocyte interstitial migration,” Seminars in Immunopathology, 2014. View at Publisher · View at Google Scholar
  • Aaron G. Day-Williams, Chao Sun, Ilijas Jelcic, Helen McLaughlin, Tim Harris, Roland Martin, and John P. Carulli, “Whole Genome Sequencing Reveals a Chromosome 9p Deletion Causing DOCK8 Deficiency in an Adult Diagnosed with Hyper IgE Syndrome Who Developed Progressive Multifocal Leukoencephalopathy,” Journal of Clinical Immunology, 2014. View at Publisher · View at Google Scholar
  • Sevgi Keleş, and Talal Chatila, “Combined immunodeficiency due to DOCK8 deficiency: A tribute to Prof. Isil Berat Barlan, M.D,” Turkish Journal of Immunology, vol. 3, no. 2, pp. 76–83, 2015. View at Publisher · View at Google Scholar
  • Kerry Dobbs, Cecilia Domínguez Conde, Shen-Ying Zhang, Silvia Parolini, Magali Audry, Janet Chou, Emma Haapaniemi, Sevgi Keles, Ivan Bilic, Satoshi Okada, Michel J. Massaad, Samuli Rounioja, Adel M. Alwahadneh, Nina K. Serwas, Kelly Capuder, Ergin Çiftçi, Kerstin Felgentreff, Toshiro K. Ohsumi, Vincent Pedergnana, Bertrand Boisson, Şule Haskoloğlu, Arzu Ensari, Michael Schuster, Alessandro Moretta, Yuval Itan, Ornella Patrizi, Flore Rozenberg, Pierre Lebon, Janna Saarela, Mikael Knip, Slavé Petrovski, David B. Goldstein, Roberta E. Parrott, Berna Savas, Axel Schambach, Giovanna Tabellini, Christoph Bock, Talal A. Chatila, Anne Marie Comeau, Raif S. Geha, Laurent Abel, Rebecca H. Buckley, Aydan İkincioğulları, Waleed Al-Herz, Merja Helminen, Figen Doğu, Jean-Laurent Casanova, Kaan Boztuğ, and Luigi D. Notarangelo, “Inherited DOCK2 Deficiency in Patients with Early-Onset Invasive Infections,” New England Journal of Medicine, vol. 372, no. 25, pp. 2409–2422, 2015. View at Publisher · View at Google Scholar
  • Alexandra F. Freeman, and Kenneth N. Olivier, “Hyper-IgE Syndromes and the Lung,” Clinics in Chest Medicine, 2016. View at Publisher · View at Google Scholar
  • Bluma J Lesch, Sherman J Silber, John R McCarrey, and David C Page, “Parallel evolution of male germline epigenetic poising and somatic development in animals,” Nature Genetics, 2016. View at Publisher · View at Google Scholar
  • Sevgi Keles, Louis Marie Charbonnier, Venkataraman Kabaleeswaran, Ismail Reisli, Ferah Genel, Nesrin Gulez, Waleed Al-Herz, Narayanaswamy Ramesh, Antonio Perez-Atayde, Neslihan Karaca Eeder, Necil Kutukculer, Hao Wu, Raif S. Geha, and Talal A. Chatila, “Dedicator of cytokinesis 8 regulates signal transducer and activator of transcription 3 activation and promotes TH17 cell differentiation,” Journal of Allergy and Clinical Immunology, 2016. View at Publisher · View at Google Scholar
  • Sol A Ban, Hsiang Ting Hsu, Deniz Cagdas, Johannes B Huppa, Loïc Dupré, Ulrich Jäger, Michael Sixt, Ilhan Tezcan, Jordan S Orange, Miroslav Hons, Kaan Boztug, Emily M MacE, Özlem Yüce Petronczki, René Platzer, Laurène Pfajfer, Ivan Bilic, Elisabeth Salzer, Katharina L Willmann, Malini Mukherjee, Verena Supper, Pinaki P Banerjee, Papiya Sinha, Fabienne McClanahan, Gerhard J Zlabinger, Winfried F Pickl, John G Gribben, Hannes Stockinger, Keiryn L Bennett, Özden Sanal, and Wojciech Garncarz, “RASGRP1 deficiency causes immunodeficiency with impaired cytoskeletal dynamics,” Nature Immunology, vol. 17, no. 12, pp. 1352–1360, 2016. View at Publisher · View at Google Scholar
  • Catherine M. Biggs, Sevgi Keles, and Talal A. Chatila, “DOCK8 deficiency: Insights into pathophysiology, clinical features and management,” Clinical Immunology, 2017. View at Publisher · View at Google Scholar
  • Fayhan J. Alroqi, Louis-Marie Charbonnier, Sevgi Keles, Fatima Ghandour, Pierre Mouawad, Rami Sabouneh, Reem Mohammed, Abduarahman Almutairi, Janet Chou, Michel J. Massaad, Raif S. Geha, Zeina Baz, and Talal A. Chatila, “DOCK8 Deficiency Presenting as an IPEX-Like Disorder,” Journal of Clinical Immunology, 2017. View at Publisher · View at Google Scholar
  • Dimana Dimitrova, and Alexandra F. Freeman, “Current Status of Dedicator of Cytokinesis-Associated Immunodeficiency,” Dermatologic Clinics, vol. 35, no. 1, pp. 11–19, 2017. View at Publisher · View at Google Scholar
  • Di Chen, Bing Xu, Lin Zhou, Zhijie Lei, Daiming Fan, Rui Wang, Yi Chu, Xiaowei Li, Kaichun Wu, Jie Liang, Mingzuo Jiang, Weijie Wang, Yongzhan Nie, and Yulong Shang, “MiR-148b-3p inhibits gastric cancer metastasis by inhibiting the Dock6/Rac1/Cdc42 axis,” Journal of Experimental and Clinical Cancer Research, vol. 37, no. 1, 2018. View at Publisher · View at Google Scholar
  • Marianne Burbage, Francesca Gasparrini, Shweta Aggarwal, Mauro Gaya, Johan Arnold, Usha Nair, Michael Way, Andreas Bruckbauer, and Facundo D Batista, “Tuning of in vivo cognate B-T cell interactions by Intersectin 2 is required for effective anti-viral B cell immunity,” eLife, vol. 7, 2018. View at Publisher · View at Google Scholar