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Disease Markers
Volume 30, Issue 4, Pages 181-190
http://dx.doi.org/10.3233/DMA-2011-0767

A Simple Oligonucleotide Biochip Capable of Rapidly Detecting Known Mitochondrial DNA Mutations in Chinese Patients with Leber’S Hereditary Optic Neuropathy (LHON)

Wei-Dong Du,1,6 Gang Chen,1,2 Hui-Min Cao,2 Qing-Hui Jin,2 Rong-Feng Liao,3 Xiang-Cheng He,4 Da-Ben Chen,5 Shu-Ren Huang,4 Hui Zhao,2 Yong-Mei Lv,1 Hua-Yang Tang,1 Xian-Fa Tang,1 Yong-Qing Wang,4 Song Sun,5 Jian-Long Zhao,2 and Xue-Jun Zhang1

1Key Lab of Gene Resource Utilization for Severe Hereditary Diseases of Ministry of Education of China & Key Lab of Genome Research of Anhui Province, Anhui Medical University, 230032 Hefei, China
2Shanghai Institute of Microsystem and Information Technology, Chinese Academy of Sciences, 200050 Shanghai, China
3Department of Ophthalmology, the First Affiliated Hospital of Anhui Medical University, 230032 Hefei, China
4Ophthalmology Hospital, Red Cross Association of Anhui Province, 230022 Hefei, China
5Department of Ophthalmology, University of Science and Technology of China, 230026 Hefei, China
6Sektion Experimentelle Anaesthesiologie, Universitaetsklinikum Ulm, Steinhoevelstrasse 9, 89075 Ulm, Germany

Received 17 June 2011; Accepted 17 June 2011

Copyright © 2011 Hindawi Publishing Corporation. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

How to Cite this Article

Wei-Dong Du, Gang Chen, Hui-Min Cao, et al., “A Simple Oligonucleotide Biochip Capable of Rapidly Detecting Known Mitochondrial DNA Mutations in Chinese Patients with Leber’S Hereditary Optic Neuropathy (LHON),” Disease Markers, vol. 30, no. 4, pp. 181-190, 2011. https://doi.org/10.3233/DMA-2011-0767.