Chemokines and Chemokine Receptors in Susceptibility to HIV-1 Infection and Progression to AIDS

Chatterjee, Animesh; Rathore, Anurag; Vidyant, Sanjukta; Kakkar, Kavita; Dhole, Tapan N.

doi:https://doi.org/10.3233/DMA-2011-0874

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Review | Open Access

Volume 32 | Article ID 147148 | https://doi.org/10.3233/DMA-2011-0874

Chemokines and Chemokine Receptors in Susceptibility to HIV-1 Infection and Progression to AIDS

Animesh Chatterjee,¹Anurag Rathore,¹Sanjukta Vidyant,¹Kavita Kakkar,¹and Tapan N. Dhole¹

Received23 Feb 2012

Accepted23 Feb 2012

Abstract

A multitude of host genetic factors plays a crucial role in susceptibility to HIV-1 infection and progression to AIDS, which is highly variable among individuals and populations. This review focuses on the chemokine-receptor and chemokine genes, which were extensively studied because of their role as HIV co-receptor or co-receptor competitor and influences the susceptibility to HIV-1 infection and progression to AIDS in HIV-1 infected individuals.

Copyright

Copyright © 2012 Hindawi Publishing Corporation. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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