Research Article

Positive Association between GCKR rs780093 Polymorphism and Coronary Heart Disease in the Aged Han Chinese

Table 6

A breakdown association test between cases and controls by agea.

Agers780093Genotype (counts) (df = 2)HWEAllele (counts) (df = 1)OR (95% CI)
GGGAAAGA

≤55Cases ( ) 2573400.49 123153
Controls ( ) 44100422.440.300.38 1881842.26 0.13 0.79 (0.58–1.08)
55–65Cases ( )5294540.40 198202
Controls ( ) 4396480.790.670.77 1821920.05 0.82 1.03 (0.78–1.37)
≥65Cases ( )49130520.07 228234
Controls ( )2256436.860.030.71 1001424.11 0.04 1.38 (1.01–1.89)

HWE: Hardy-Weinberg equilibrium; OR: odds ratio; CI: confidence interval.