Research Article
Positive Association between GCKR rs780093 Polymorphism and Coronary Heart Disease in the Aged Han Chinese
Table 6
A breakdown association test between cases and controls by agea.
| Age | rs780093 | Genotype (counts) | | (df = 2) | HWE | Allele (counts) | | (df = 1) | OR (95% CI) | GG | GA | AA | | | | G | A | | | |
|
≤55 | Cases () | 25 | 73 | 40 | | | 0.49 | 123 | 153 | | | | Controls () | 44 | 100 | 42 | 2.44 | 0.30 | 0.38 | 188 | 184 | 2.26 | 0.13 | 0.79 (0.58–1.08) | 55–65 | Cases () | 52 | 94 | 54 | | | 0.40 | 198 | 202 | | | | Controls () | 43 | 96 | 48 | 0.79 | 0.67 | 0.77 | 182 | 192 | 0.05 | 0.82 | 1.03 (0.78–1.37) | ≥65 | Cases () | 49 | 130 | 52 | | | 0.07 | 228 | 234 | | | | Controls () | 22 | 56 | 43 | 6.86 | 0.03 | 0.71 | 100 | 142 | 4.11 | 0.04 | 1.38 (1.01–1.89) |
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HWE: Hardy-Weinberg equilibrium; OR: odds ratio; CI: confidence interval.
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