Clinical Study

Investigation of Associations between Obesity and LEP G2548A and LEPR 668A/G Polymorphisms in a Turkish Population

Table 3

Distribution of LEPR gene 668 A/G polymorphism and allele frequencies between obesity patients and controls.

GenotypePatients
( : 127) (%)
Controls
( : 105) (%)

AA50 (39)50 (47.6)
GA56 (44)46 (43.8)0.05*
GG21 (16.5)9 (8.5)
AA + GA : GG106 : 2196 : 90.10
I GA + GG : AA77 : 5055 : 500.20
Allele frequency
A156 (61.4)146 (69.5)0.08
G 98 (38.5)64 (30.4)

 *According to Bonferroni correction is not significant.