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Disease Markers
Volume 35, Issue 5, Pages 505–511
Research Article

Procalcitonin Levels in Patients with Complete and Incomplete Kawasaki Disease

Department of Pediatrics, Chonnam National University Hospital, Chonnam National University Medical School, 8 Hakdong, Dong-gu, Gwangju 501-757, Republic of Korea

Received 15 July 2013; Revised 10 September 2013; Accepted 16 September 2013

Academic Editor: Natacha Turck

Copyright © 2013 Hwa Jin Cho et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.


Incomplete Kawasaki disease (iKD) is considered to be a less complete form of Kawasaki disease (cKD), and several differences in the laboratory presentations of iKD and cKD have been noted. We investigated serum procalcitonin levels in patients with iKD, cKD, and other febrile diseases (a control group). Seventy-seven patients with cKD, 24 with iKD, and 41 controls admitted to our hospital from November 2009 to November 2011 were enrolled in the present study. We obtained four measurements of serum procalcitonin levels and those of other inflammatory markers from each patient. Samples were taken for analysis on the day of diagnosis (thus before treatment commenced; D0) and 2 (D2), 14 (D14), and 56 days (D56) after intravenous immunoglobulin infusion. We obtained control group data at D0. The mean D0 serum procalcitonin levels of cKD patients (  ng/mL) and controls (  ng/mL) were significantly higher than those of iKD patients (  ng/mL) ( and , resp.). No significant difference in mean procalcitonin level was evident among groups at any subsequent time. In conclusion, the serum procalcitonin level of patients with acute-stage cKD was significantly higher than that of iKD patients.