HLA Markers for Poor Prognosis in Systemic Sclerosis Brazilian Patients

Table 4

Risk and protective alleles for pulmonary fibrosis.

PF-related alleles	PR	(95% CI)	𝑃^∗
HLA-A*30	1.86	(1.26–2.74)	0.020
HLA-DQB1*04	1.70	(1.17–2.48)	0.019
HLA-DQB1*05	0.41	(0.24–0.72)	<0.001
HLA-DRB1*01	0.38	(0.17–0.85)	0.004

95% CI: 95% confidence intervals; PR: prevalence ratio; *univariate 𝑃 values calculated with Chi-square and Fisher’s exact tests where appropriate.
The PR and 𝑃 values ​ ​were obtained by comparing patients with and without PF and PAH.