Brain Hypothermic Therapy Dramatically Decreases Elevated Blood Concentrations of High Mobility Group Box 1 in Neonates with Hypoxic-Ischemic Encephalopathy

Table 2

HMGB1 level comparison between the BHT (+) and BHT (−) groups.

	BHT (−) 𝑛=5 (ng/mL)	BHT (+) 𝑛=8 (ng/mL)	𝑃
Admission	24.1±10.8	85.7±55.8	0.037
1 day after birth	61.6±32.4	7.9±5.1	0.0026
5 days after birth	7.7±5.0	8.9±7.7	NS

Data are means ± standard deviation.
BHT: brain hypothermic therapy.