Disease Markers / 2013 / Article / Tab 1

Research Article

Urinary Leukotriene E4 Is Associated with Renal Function but Not with Endothelial Function in Type 2 Diabetes

Table 1

Baseline characteristics of total study group and tertiles based on glomerular filtration rate.

Total study group
eGFR >90 
eGFR 90–60 
eGFR <60 
value

Male, %80758083
Age, years65 (48, 78)60 (50, 78)60 (48, 67)66 (54, 75)0.29
BMI, kg/m230.7 (25, 40.9)29.7 (25.0, 36.3)32.1 (28.1, 35.3)31.0 (26.2, 40.9)0.67
Waist circumference, cm113 (95, 133)116 (101, 122)115 (100, 121)111 (95, 133)0.55
Systolic blood pressure, mmHg140 (80, 185)140 (130, 180)138 (80, 185)148 (115, 180)0.71
Diastolic blood pressure, mmHg80 (50, 90)80 (70, 90)80 (50, 90)75 (60, 90)0.46
Creatinine, mol/L87.5 (49, 483)75 (49, 87)85 (78, 104)169 (81, 483)<0.0001
eGFR, mL/min71 (14, 129)110 (91, 129)75 (61, 88)41 (14, 55)<0.0001
Cholesterol, mmol/L3.6 (2.2, 6.9)3.7 (3.1, 6.9)3.4 (2.2, 4.4)3.7 (2.6, 5.0)0.31
LDL cholesterol, mmol/L2.1 (1.0, 5.0)2.3 (1.8, 5.0)2.0 (1.1, 3.1)2.4 (1.0, 3.2)0.34
HDL cholesterol, mmol/L0.8 (0.6, 1.4)0.9 (0.7, 1.4)0.8 (0.6, 1.4)0.8 (0.6, 1.2)0.39
Triglycerides, mmol/L1.3 (0.8, 2.4)1.3 (0.8, 2.3)1.4 (0.8, 2.2)1.4 (2.4, 0.8)0.87
HbA1c, mmol/mol45.4 (27.9, 83.6)53.6 (28.9, 62.8)44.3 (27.9, 68.3)46.5 (29.0, 83.6) 0.56
Peripheral arterial tonometry, RHI1.60 (1.28, 3.19)1.50 (1.39, 3.19)1.58 (1.28, 2.14)1.66 (1.35, 2.38)0.84
Flow mediated vasodilatation, %2.0 (0, 10.9)1.9 (0.7, 10.9)4.1 (1.2, 8.7)1.5 (0, 4.8)0.036
hsCRP, mg/L1.9 (0.3, 15)2.3 (0.4, 14)2.0 (0.3, 6.6)1.4 (0.3, 15.0)0.88
U-LTE4 (pg/mg creatinine)197 (13, 483)332 (156, 483)184 (29, 470)177 (13, 390)0.049

Data shown as median (min, max).