484959.fig.002a
(a)
484959.fig.002b
(b)
Figure 2: Axial volumetric T1 weighted images of a relapsing-remitting (RR) MS patient with EDSS = 1.5 (a) and of a secondary progressive (SP) MS patient with EDSS = 5.5 (b). The SP patient showed significant whole brain and grey matter atrophy compared to RR patient.