Multivariate Path Analysis of Serum 25-Hydroxyvitamin D Concentration, Inflammation, and Risk of Type 2 Diabetes Mellitus

Table 4

Standardized path coefficients and 95% confidence intervals by sex.

Path	Path coefficient	95% CI		𝑃  value*
Males
Standardized effects on HbA1c
25(OH)D→HbA1c	−0.05	−0.08	−0.02	0.003
Log-CRP→ HbA1c	0.09	0.06	0.12	<0.0001
Standardized effects on log-CRP
25(OH)D→Log-CRP	−0.09	−0.12	−0.06	<0.0001
Standardized effects on 25(OH)D
WC→ 25(OH)D	−0.18	−0.21	−0.15	<0.0001
Race→ 25(OH)D	−0.41	−0.44	−0.39	<0.0001
Females
Standardized effects on HbA1c
25(OH)D→HbA1c	0.004	−0.03	0.03	0.28
Log-CRP→ HbA1c	0.05	0.02	0.07	0.0004
Standardized effects on Log-CRP
25(OH)D→Log-CRP	−0.13	−0.16	−0.10	<0.0001

25(OH)D: 25-hydroxyvitamin D, WC: waist circumference, log-CRP: log C-reactive protein.
^∗𝑃 value based on two-tailed test.