Research Article

Mutation of NPM1 and FLT3 Genes in Acute Myeloid Leukemia and Their Association with Clinical and Immunophenotypic Features

Table 4

Relationship of FLT3 and NPM1 mutations with translocations.

Translocation ( )NPM1 mut. % (22)NPM1 wild % (98)P valueFLT3 mut. % (31)FLT3 wild % (89)P value

BCR/ABL (11)4 (1)10 (10)0.686 (2)10 (9)0.72
PML/RARα (5)4 (1)4 (4)1.03 (1)5 (4)1.0
AML/ETO (28)14 (3)25 (25)0.2711 (3)28 (25)0.04 *

Bold significant P-value = 0.02.