A Semiautomated Framework for Integrating Expert Knowledge into Disease Marker Identification

Figure 3

The comparative results in the optimal CAs between the BALF (solid lines) and plasma (dashed lines) from the Ada-deficient mice during the disease developmental course. The CAs were derived from the cumulatively (blue) and individually (green) significantly changed proteins at different time points. The CAs were obtained from the resulting clusters using the joint distance matrix of protein expression patterns and their functional relationships (XOA).