Impact of IL12B Gene rs 3212227 Polymorphism on Fibrosis, Liver Inflammation, and Response to Treatment in Genotype 4 Egyptian Hepatitis C Patients

Table 1

Demographic data and clinical investigations of 133 HCV infected patients.

Variables	133 chronic HCV patients
Age (years)	42.5±9.7
BMI (Kg/m^2)	27.1±4.0
Hemoglobin (g/dL)	13.9±1.6
Platelet count (10³/μL)	216±67.2
Baseline ALT (IU/L)	68.3±42.9
Baseline AST (IU/L)	55.6±37.4
Total bilirubin (mg/dL)	0.62±0.39
Total leukocytic count (10³/μL)	6.08±2.08
Gender
Male	91 (68.4%)
Female	42 (31.6%)
AFP (cut off)
≤4.5 (ng/mL)	83 (62.4%)
>4.5 (ng/mL)	50 (37.6%)
HCV viral load
<600,000 IU/mL	80 (60.1%)
≥600,000 IU/mL	53 (39.9%)
Liver histology (METAVIR)
F (n: 0/1/2/3/4)	2/59/29/36/7
A (n: 0/1/2/3)	7/81/33/12

BMI: body mass index; ALT: alanine aminotransferase; AST: aspartate amino transferase; AFP: alpha-fetoprotein; F: liver fibrosis stage; A: liver activity grade.