Research Article
Impact of IL12B Gene rs 3212227 Polymorphism on Fibrosis, Liver Inflammation, and Response to Treatment in Genotype 4 Egyptian Hepatitis C Patients
Table 1
Demographic data and clinical investigations of 133 HCV infected patients.
| Variables | 133 chronic HCV patients |
| Age (years) | | BMI (Kg/m2) | | Hemoglobin (g/dL) | | Platelet count (10³/μL) | | Baseline ALT (IU/L) | | Baseline AST (IU/L) | | Total bilirubin (mg/dL) | | Total leukocytic count (10³/μL) | |
| Gender | | Male | 91 (68.4%) | Female | 42 (31.6%) |
| AFP (cut off) | | 4.5 (ng/mL) | 83 (62.4%) | 4.5 (ng/mL) | 50 (37.6%) |
| HCV viral load | | 600,000 IU/mL | 80 (60.1%) | 600,000 IU/mL | 53 (39.9%) |
| Liver histology (METAVIR) | | F (n: 0/1/2/3/4) | 2/59/29/36/7 | A (n: 0/1/2/3) | 7/81/33/12 |
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BMI: body mass index; ALT: alanine aminotransferase; AST: aspartate amino transferase; AFP: alpha-fetoprotein; F: liver fibrosis stage; A: liver activity grade.
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