Association between Angiotensin II Type 1 Receptor Polymorphism and Sudden Cardiac Death in Myocardial Infarction

Table 2

Distributions of demographic and relevant clinical risk factors between ACS patients and healthy controls and the estimated OR for each risk factor.

Subject characteristics	ACS patients; (𝑛=749)	Controls; (𝑛=627)	Univariate analysis	P	Multivariate analysis	P
			OR (95% CI)		OR (95% CI)
AT1R-genotypes
AA	241	316	1 (ref.)		1 (ref.)
AC	329	269	1.17 (0.79–2.1)	0.603	1.284 (0.595–2.773)	0.524
CC	179	42	2.76 (1.07–6.49)	0.004	4.295 (1.436–12.851)	0.009
Mean age	61.4±9.7	54±10.3	0.75 (0.24–2.76)	0.98	1.25 (0.46–2.96)	0.425
Sex—male	432	354	1.53 (0.89–2.62)	0.123	—	—
Systolic blood pressure ≥ 140 mmHg	327	97	9.73 (3.44–17.16)	<0.001	6.97 (2.53–14.37)	0.003
Diastolic blood pressure ≥ 90 mmHg	94	23	5.92 (1.47–9.81)	0.002	3.65 (1.45–10.40)	0.004
Diabetes mellitus	329	0	14.22 (4.98–25.26)	<0.001	12.75 (3.41–23.58)	0.001