Research Article
Expression and Clinical Significance of Livin Protein in Hepatocellular Carcinoma
Table 2
Correlation between livin protein expression and clinicopathological characteristics of hepatocellular carcinoma.
| Clinico-pathological characteristics | | | Livin protein expression in tissues | | | | Livin protein expression in blood plasma | value | | | No. cases | No. positives | No. negatives | value | value | No. cases | No. cases with high expression | No. cases with low expression |
| Age (years) | 55 | 28 | 19 | 9 | 0.047 | 0.05 | 16 | 6 | 10 | 0.05 | 55 | 22 | 13 | 9 | 15 | 10 | 5 | Cirrhosis | Positive | 44 | 24 | 20 | | 0.05 | | | | | Negative | 6 | 3 | 3 | | | | | | HBsAg | Positive | 41 | 26 | 15 | | 0.05 | 20 | 10 | 10 | 0.05 | Negative | 9 | 5 | 4 | | 11 | 4 | 6 | HBcAb | Positive | 49 | 26 | 23 | | 0.05 | | | | | Negative | 1 | 1 | 0 | | | | | | AFP (ng/mL) | 400 | 20 | 13 | 7 | 0.019 | 0.05 | 13 | 5 | 8 | 0.05 | 400 | 30 | 19 | 11 | 18 | 11 | 7 | Tumor diameter (cm) | 3 | 7 | 5 | 2 | | 0.05 | 12 | 8 | 4 | 0.05 | 3 | 43 | 18 | 25 | | 19 | 8 | 11 | Growth pattern | Infiltration | 28 | 15 | 13 | 3.029 | 0.05 | 14 | 7 | 7 | 0.05 | Expansion | 22 | 17 | 5 | 17 | 9 | 8 | | Degree of differentiation | High | 18 | 12 | 6 | 0.467 | 0.05 | 14 | 7 | 7 | 0.05 | Moderate | 23 | 14 | 9 | 14 | 7 | 7 | Low | 9 | 6 | 3 | 3 | 2 | 1 | Recurrence and metastasis | Yes | 25 | 15 | 10 | 0.471 | 0.05 | 17 | 8 | 9 | 0.05 | No | 25 | 17 | 8 | 14 | 7 | 7 |
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