Comparison of the Diagnostic Accuracy of the MSLN Gene Products, Mesothelin and Megakaryocyte Potentiating Factor, as Biomarkers for Mesothelioma in Pleural Effusions and Serum

Figure 1

Biomarker concentrations in pleural effusions: (a) MPF as determined using assay from MBL; (b) soluble mesothelin concentrations; (c) correlation between MPF concentrations determined by MBL assays and mesothelin; and (d) Receiver Operating Characteristic (ROC) curves showing accuracy of effusion biomarkers in differentiating all patients with MM (𝑛=43) from all other cases (𝑛=222). (Significant difference between indicated cohorts: ***𝑃<0.0001.)

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