Research Article
Nuclear Expression of Snail Is an Independent Negative Prognostic Factor in Human Breast Cancer
Table 2
Association between Snail expression and clinicopathological parameters.
| Clinicopathologic parameter | Snail positive | Snail negative | value |
| Mean tumor size (mm) ± SD | | |
<0.0001 | Mean age at diagnosis (years) ± SD | | | 0.9164 |
| | () | | | | |
| Tumor stage | | | | | <0.0001 | pT1 | 47 | 15.3 | 260 | 84.7 | pT2 | 128 | 23.5 | 416 | 76.5 | pT3 | 20 | 28.2 | 51 | 71.8 | pT4 | 70 | 57.8 | 51 | 42.2 | Lymph node involvement | | | | | <0.0001 | pN0 | 115 | 20.7 | 440 | 79.3 | pN1 | 103 | 25.9 | 295 | 74.1 | pN2 | 47 | 54.0 | 40 | 46.0 | Tumor grade | | | | | <0.0001 | 1 | 28 | 11.0 | 226 | 89.0 | 2 | 59 | 13.4 | 380 | 86.6 | 3 | 178 | 50.9 | 172 | 49.1 | Estrogen receptor | | | | | <0.0001 | ER+ | 102 | 13.0 | 685 | 87.0 | ER− | 163 | 64.4 | 90 | 35.6 | HER2 | | | | | 0.1266 | HER2+ | 59 | 29.6 | 140 | 70.4 | HER2− | 206 | 24.4 | 638 | 75.6 | Ki67 | | | | | <0.0001 | Ki67+ | 229 | 28.5 | 574 | 71.5 | Ki67− | 35 | 15.0 | 198 | 85.0 |
|
|