RNA-Seq Data Mining: Downregulation of NeuroD6 Serves as a Possible Biomarker for Alzheimer’s Disease Brains

Figure 2

IPA pathways of the core set of 522 DEGs in the frontal cortex of AD identified by RNA-Seq data analysis. Entrez Gene IDs of 522 DEGs in the frontal cortex of AD identified by RNA-Seq data analysis of SRA060572 were imported into the Core Analysis tool of IPA. It extracted the most significant functional network termed “Hereditary Disorder, Neurological Disease, Psychological Disorders” relevant to the set of imported genes. Downregulated DEGs are colored green, while upregulated DEGs are colored red. NeuroD6 is highlighted by a blue circle.