The Clinicopathologic Importance of Serum Lactic Dehydrogenase in Patients with Gastric Cancer

Table 3

Univariate and multivariate analyses of prognostic variables in gastric cancer patients.

Parameters	Univariate analysis	Multivariate analysis
		HR (95% CI)
OS
Age (≥60)	0.676	—	0.800
Gender	0.076	—	0.226
SLDH	<0.001^*	2.476 (1.450–4.228)	0.001^*
Tumor size	0.112	—	0.105
Borrmann type	0.329	—	0.070
Histological type	0.561	—	0.521
pT stage	<0.001^*	—	0.322
pN stage	0.004^*	—	0.630
pM stage	<0.001^*	2.157 (1.454–3.201)	<0.001^*
pTNM	<0.001^*	1.920 (1.548–2.381)	<0.001^*
DFS
Age (≥60)	0.680	—	0.938
Gender	0.097	—	0.250
SLDH	<0.001^*	2.209 (1.292–3.778)	0.004^*
Tumor size	0.785	—	0.136
Borrmann type	0.381	—	0.061
Histological type	0.632	—	0.475
pT stage	<0.001^*	—	0.197
pN stage	0.002^*	—	0.455
pM stage	<0.001^*	1.926 (1.306–2.840)	0.001^*
pTNM	<0.001^*	1.880 (1.516–2.330)	<0.001^*

CI: confidence interval; HR: hazard ratio; OS: overall survival; DFS: disease-free survival; p: pathological.
SLDH: serum lactate dehydrogenase. .