Association of Polymorphisms of Genes Involved in Lipid Metabolism with Blood Pressure and Lipid Values in Mexican Hypertensive Individuals

Table 1

Frequencies of genotypic and allelic polymorphisms in hypertensive and normotensive subjects.

	APOA5 p.S19W			APOB p.E4181K			FABP2 p.A55T			LDLR c.1959C>T			LIPC −514C>T			LPL p.S474X			MTTP −493 G>T
HT			%			%			%			%			%			%			%
Genotype	SS	97	60.6	EE	88	55.0	AA	57	36.1	CC	36	22.5	CC	38	24.7	SS	142	88.8	GG	106	67.1
	SW	56	35.0	EK	67	41.9	AT	47	29.7	CT	73	45.6	CT	67	43.5	SX	17	10.6	GT	48	30.4
	WW	7	4.4	KK	5	3.1	TT	54	34.2	TT	51	31.9	TT	49	31.8	XX	1	0.6	TT	4	2.5
			%			%			%			%			%			%			%
Allele	S	250	77.1	E	243	75.9	A	161	50.9	C	145	45.3	C	143	46.4	S	301	94.1	G	260	82.3
	W	70	22.9	K	77	24.1	T	155	49.1	T	175	54.7	T	165	53.6	X	19	5.9	T	56	17.7
NT			%			%			%			%			%			%			%
Genotype	SS	100	62.5	EE	111	69.4	AA	71	44.7	CC	34	21.2	CC	35	22.3	SS	135	84.9	GG	112	70.4
	SW	53	33.1	EK	42	26.3	AT	35	22.0	CT	82	51.3	CT	78	49.7	SX	22	13.8	GT	42	26.4
	WW	7	4.4	KK	7	4.3	TT	53	33.3	TT	44	27.5	TT	44	28.0	XX	2	1.3	TT	5	3.2
			%			%			%			%			%			%			%
Allele	S	253	79.1	E	264	82.5	A	177	55.7	C	150	46.9	C	148	47.1	S	292	91.8	G	266	83.6
	W	67	20.9	K	56	17.5	T	141	44.3	T	170	53.1	T	166	52.9	X	26	8.2	T	52	16.4
genotype	0.93			0.01			0.19			0.58			0.52			0.77			0.82
allele	0.85			0.04			0.23			0.69			0.86			0.27			0.65

Due to a lack of DNA, these samples were not screened. HT: hypertensive patients. NT: normotensive subjects.