Functional Polymorphisms of Matrix Metalloproteinases 1 and 9 Genes in Women with Spontaneous Preterm Birth

Table 5

The association of genotypes and alleles of MMP-1-1607 1G/2G and MMP-9-1562 C/T gene polymorphisms with familial and isolated SPTB according to dominant, recessive, and codominant genetic models.

Gene	Genetic model	SPTB in family versus isolated SPTB
		OR (95% CI)
MMP-1-1607	Dominant
	1G1G + 1G2G versus 2G2G	0.78 (0.29–0.07)	0.620
	Recessive
	1G1G versus 1G2G + 2G2G	1.08 (0.39–2.92)	0.885
	Codominant
	1G1G versus 2G2G	0.87 (0.25–3.03)	0.833
	1G1G versus 1G2G	1.17 (0.41–3.33)	0.774
	2G2G versus 1G2G	1.33 (0.48–3.69)	0.579
	Alleles
	1G versus 2G	0.94 (0.53–1.68)	0.837
MMP-9-1562	Dominant
	CC + CT versus TT	0.44 (0.01–22.84)	0.686
	Recessive
	CC versus CT + TT	0.57 (0.23–1.46)	0.245
	Codominant
	CC versus TT	0.39 (0.01–20.15)	0.639
	CC versus CT	0.57 (0.23–1.46)	0.245
	TT versus CT	1.48 (0.03–80.40)	0.849
	Alleles
	C versus T	0.62 (0.26–1.47)	0.279