Research Article
High SHIP2 Expression Indicates Poor Survival in Colorectal Cancer
Table 1
The relationship between SHIP2 expression and clinical attributes of 102 CRC patients.
| Groups | Number | SHIP2 | | value | + | % |
| Gender | | | | | | Male | 63 | 31 | 49.2 | 0.04 | 0.839 | Female | 39 | 20 | 51.3 | Age (years) | | | | | | ≥60 | 68 | 34 | 50.0 | 0.00 | 1.000 | <60 | 34 | 17 | 50.0 | Tumor size (cm) | | | | | | ≥5 | 44 | 21 | 47.7 | 0.16 | 0.689 | <5 | 58 | 30 | 51.7 | Tumor location | | | | | | Colon | 87 | 43 | 49.4 | 1.10 | 0.576 | Rectum | 11 | 5 | 45.5 | Ileocecal junction | 4 | 3 | 75.0 | Histological type | | | | | | Adenocarcinoma | 99 | 48 | 48.5 | 3.09 | 0.079 | Nonadenocarcinoma | 3 | 3 | 100.0 | Tumor differentiation | | | | | | Well | 4 | 1 | 25.0 | 1.32 | 0.518 | Moderately | 82 | 44 | 53.7 | Poorly | 7 | 4 | 57.1 | Insufficient data | 9 | 2 | | Serum CEA level (ng/mL) | | | | | | ≥15 | 11 | 6 | 54.5 | 0.30 | 0.581 | <15 | 59 | 25 | 42.4 | Insufficient data | 32 | 20 | | Lymph node metastasis | | | | | | Positive | 34 | 22 | 64.7 | 4.41 | 0.036* | Negative | 68 | 29 | 42.6 | Distant metastasis | | | | | | Positive | 19 | 17 | 89.5 | 14.55 | 0.001* | Negative | 83 | 34 | 41.0 | TNM stage | | | | | | Stages I, II | 63 | 27 | 42.9 | 3.36 | 0.067 | Stages III, IV | 39 | 24 | 61.5 | Overall survival | | | | | | Survival | 61 | 24 | 39.3 | 6.89 | 0.009* | Death | 41 | 27 | 65.9 |
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