The Serum Glycome to Discriminate between Early-Stage Epithelial Ovarian Cancer and Benign Ovarian Diseases
Figure 1
MALDI-TOF-MS spectra of permethylated N-glycans from (a) a patient with early-stage primary EOC, (b) a patient with benign ovarian disease, and (c) a healthy volunteer. Measurements were performed in the positive-ion mode. All ions are present in their sodiated form [M+Na]+. The monosaccharides are depicted as follows: Man, dark gray circle; Gal, light gray circle; GlcNAc, black square; Fuc, dark gray triangle; Neu5Ac, dark gray diamond; dark gray star polygon, underpermethylated; light gray star polygon, nonidentified.
