The Serum Glycome to Discriminate between Early-Stage Epithelial Ovarian Cancer and Benign Ovarian Diseases

Table 1

Primary serous epithelial ovarian cancer patient demographics.

	Healthy controls	BOD patients	EOC patients
Number of patients	33	20	20
Age
Mean	52	57	57
Median	50	52	58
Range	40–81	35–97	40–78
SD	10.08	14.36	10.46
Stage
I	—	—	10
II	—	—	10
Grade
1	—	—	1
2	—	—	10
3	—	—	9
GLYCOV value*
Mean	0.21	0.42	4.31
Median	0.13	0.38	2.90
Range	0.00–0.83	0.02–1.27	0.56–12.82
SD	0.21	0.29	3.84
CA125 (kU/L)
Mean	14.45	36.90	225.86
Median	12.00	30.50	65.50
Range	6–38	12–100	6–1474
SD	6.92	24.36	375.87

*GLYCOV values were calculated using the relative areas obtained from the MALDI-TOF-MS spectra: (sum of relative areas of 3776.8, 3950.9, 4226.1, 4400.2, 4587.4, 4761.5, 4935.7)// (sum of relative areas of 1579.7, 1783.8, 1987.9 and 2192.0).